Neurofilament Light Chain (tNfL-FZJ-1) Aptamer Details
ID# 9978
Structure
Chemistry
DNA
Target
Neurofilament Light Chain
Category
Protein
Affinity (Kd)
181.7 nM
Length
43
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdCpdApdTpdApdCpdTpdTpdGpdCpdGpdApdGpdTpdCpdCpdTpdApdApdCpdApdGpdGpdTpdApdTpdTpdGpdGpdTpdCpdApdApdGpdGpdTpdApdCpdGpdApdTpdTpdGp-3'
Molecular Weight: 13297.7 g/mole
Extinction Coefficient: 422200
Binding Conditions / Buffer
50 mM Tris-Acetate buffer, pH = 8.2, room temperature
Binding Temp: Room Temperature°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Hangyu Li, Qinyu Hu, Krisztina Percze, Mateo Alejandro Martínez Roque, Shengkai Sun, Francesca Santoro, Andreas Offenhäusser, Dirk Mayer,
A label-free electrochemical aptasensor enables ultrasensitive and specific detection of neurofilament light,
Biosensors and Bioelectronics,
Volume 311,
2026,
118884,
ISSN 0956-5663,
https://doi.org/10.1016/j.bios.2026.118884.
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