NC195–40 Aptamer Details

ID# 8884

Back to Search Results

Structure

Chemistry

DNA

Target

Cocaine

Sequence (3-char table code)

G A C U/T

5'-dApdCpdGpdApdCpdApdGpdGpdTpdTpdCpdTpdGpdApdGpdGpdApdApdTpdCpdApdApdCpdGpdTpdCpdGpdGpdTpdGpdTpdApdGpdTpdTpdGpdTpdCpdGpdTp-3'

Molecular Weight: 12407.1

Extinction Coefficient: 393500

Binding Conditions / Buffer

Selection buffer: 20 mM Tris-HCl (pH 7.4 at 25 °C), 140 mM NaCl, 4 mM KCl, 5 mM MgCl2 Physiological buffer: 20 mM Tris-HCl (pH 7.4 at 37 °C), 140 mM NaCl, 4 mM KCl, 2 mM MgCl2

Binding Temp: 25/37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Alkhamis O., Canoura J., Wu Y., Emmons N.A., Wang Y. et al. (2024). High-Affinity Aptamers for In Vitro and In Vivo Cocaine Sensing. Journal of the American Chemical Society, (146)5, 3230-3240. https://doi.org/10.1021/jacs.3c11350

Request a Quote Have your aptamer oligo synthesized by Aptagen.