N2 against amyloid β-peptide Aptamer Details
ID# 9587
Structure
Chemistry
RNA
Target
amyloid β-peptide
Category
Protein
Affinity (Kd)
21.6 µM
Length
90
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprAprUprGprUprUprCprUprAprGprGprCprGprGprUprUprGprAprUprGprAprUprAprGprCprGprUprAprUprGprCprCprAprCprUprCprUprCprCprUprGprGprGprAprCprCprCprCprCprCprGprCprCprGprGprAprUprGprGprCprCprAprCprAprUprCprCprAprGprAprGprUprAprGprCprAprUprAprAprUprUprGprAprUprCprCprGprAp-3'
Molecular Weight: 27481.4 g/mole
Extinction Coefficient: 830300
Binding Conditions / Buffer
10mM Tris-HCl, pH 7.5, containing 150mM NaCl, 5mM MgCl2
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Takahashi, T., Tada, K., & Mihara, H. (2009). RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta. Molecular bioSystems, 5(9), 986–991. https://doi.org/10.1039/b903391b
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