Aptagen

N1 Gold Aptamer Aptamer Details

ID# 9942
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Structure
N1 Gold Aptamer structure
Chemistry
DNA
Target
Planar Au(Gold)
Category
Small Organic
Affinity (Kd)
12.26 nM
Length
38
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dGpdGpdGpdApdCpdApdGpdGpdGpdCpdTpdApdGpdCpdTpdApdTpdGpdCpdApdTpdGpdTpdGpdTpdApdTpdCpdApdApdCpdApdCpdTpdCpdCpdGpdGpdGpdTpdCpdTpdApdApdTpdCpdGpdTpdTpdCpdApdTp
Molecular Weight: 21315.8 g/mole
Extinction Coefficient: 364700

Binding Conditions / Buffer

78.5°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Tapp MJN, Slocik JM, Dennis PB, Naik RR, Milam VT. Competition-Enhanced Ligand Selection to Identify DNA Aptamers. ACS Comb Sci. 2018 Oct 8;20(10):585-593. doi: 10.1021/acscombsci.8b00048. Epub 2018 Sep 28. PMID: 30189130.
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