Aptagen

Mycolactone Aptamer Aptamer Details

ID# 7972
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Structure
Mycolactone Aptamer structure
Chemistry
RNA
Target
mycolactone
Category
Protein
Affinity (Kd)
6.3 µM
Length
0
Aptazyme
No

Sequence (3-char table code)

G A C U/T
Molecular Weight:
Extinction Coefficient:

Binding Conditions / Buffer

1X concentration (1X PBS [pH 7.4] and 10 mMMgCl2)
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Sakyi, Samuel A., et al. "RNA Aptamer That Specifically Binds to Mycolactone and Serves as a Diagnostic Tool for Diagnosis of Buruli Ulcer." PLOS Negl Trop Dis 10.10 (2016): e0004950
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