MUC1 (MA3) Aptamer Details
ID# 7725
Structure
Chemistry
DNA
Target
MUC1
Category
Protein
Affinity (Kd)
38.3 nM
Length
86
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdCpdCpdGpdCpdCpdCpdApdApdApdTpdCpdCpdCpdTpdApdApdGpdApdGpdTpdCpdGpdGpdApdCpdTpdGpdCpdApdApdCpdCpdTpdApdTpdGpdCpdTpdApdTpdCpdGpdTpdTpdGpdApdTpdGpdTpdCpdTpdGpdTpdCpdCpdApdApdGpdCpdApdApdCpdApdCpdApdGpdApdCpdApdCpdApdCpdTpdApdCpdApdCpdApdCpdGpdCpdApdCpdAp-3'
Molecular Weight: 26266.08
Extinction Coefficient: 827500
Binding Conditions / Buffer
Binding Buffer: Hanks buffer with 0.1 mg/ml salmon sperm DNA and 1 mg/ml BSA.
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Y Hu et al. Novel MUC1 aptamer selectively delivers cytotoxic agent to cancer cells in vitro. PLoS ONE 7(2012): e31970.
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