MUC1-5TR-1 Aptamer Details
ID# 7916
Structure
Chemistry
DNA
Target
human breast adenocarcinoma (MCF7)
Category
Cells
Affinity (Kd)
47.3 nM
Length
72
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdGpdGp dApdGpdAp dCpdApdAp dGpdApdAp dTpdApdAp dApdCpdGp dCpdTpdCp dApdApdGp dApdApdGp dTpdGpdAp dApdApdAp dTpdGpdAp dCpdApdGp dApdApdCp dApdCpdAp dApdCpdAp dTpdTpdCp dGpdApdCp dApdGpdGp dApdGpdGp dCpdTpdCp dApdCpdAp dApdCpdAp dGpdGpdCp
Molecular Weight: 22353.64
Extinction Coefficient: 748000
Binding Conditions / Buffer
0.5M NaCl, 10mM Tris-HCl, 1mM MgCl2, in Nuclease Free Water, pH 7.5-7.6
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
John R. Stecker, Alissa A. Savage, John G. Bruno, Dana M. Garcia, Joseph R. Koke. "Dynamics and Visualization of MCF7 Adenocarcinoma Cell Death by Aptamer-C1q-Mediated Membrane Attack" Nucleic Acid Therapeutics, Vol.22, Num.4 (2012)
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