MSA52 Aptamer Details
ID# 8839
Structure
Chemistry
DNA
Target
Target spike proteins (WHS, B.1.1.7S, B.1.429S, B.1.351S, & P.1S)
Category
Protein
Affinity (Kd)
2-10 nM
Length
79
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dTpdTpdApdCpdGpdTpdCpdApdApdGpdGpdTpdGpdTpdCpdApdCpdTpdCpdCpdGpdTpdApdGpdGpdGpdTpdTpdTpdGpdGpdCpdTpdCpdCpdGpdGpdGpdCpdCpdTpdGpdGpdCpdGpdTpdCpdGpdGpdTpdCpdGpdTpdCpdTpdCpdTpdCpdGpdCpdGpdApdApdGpdCpdApdTpdCpdTpdCpdTpdTpdTpdGpdGpdCpdGpdTpdGp-3'
Molecular Weight: 24361.7
Extinction Coefficient: 715100
Binding Conditions / Buffer
50 mM HEPES, 6 mM KCl, 150 mM NaCl, 2.5
mM CaCl2, 2.5 mM MgCl2, 0.01% v/v Tween-20, pH 7.4
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Zhang Z., Li J., Gu J., Amini R., Stacey H. et al. (2022). "A Universal DNA Aptamer that Recognizes Spike Proteins of Diverse SARS-CoV-2 Variants of Concern." Chemistry- A European Journal, 28(15), https://doi.org/10.1002/chem.202200523
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