Mouse Transferrin Receptor (FB4) Aptamer Details
ID# 7816
Structure
Chemistry
RNA
Target
Mouse Transferrin Receptor (mTfR)
Category
Protein
Affinity (Kd)
N/A nM
Length
79
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprCprGprAprAprUprUprCprCprGprCprGprUprGprUprGprCprUprGprAprGprGprGprCprGprGprAprAprGprAprAprCprUprAprAprUprUprUprGprGprGprAprCprGprGprAprUprUprGprCprGprGprCprCprGprUprUprGprUprCprUprGprUprGprGprCprGprUprCprCprGprUprUprCprGprGprGp-3'
Molecular Weight: 25651.39
Extinction Coefficient: 765200
Binding Conditions / Buffer
RNA binding buffer (20 mM NaPO4, pH 7.4/120 mM NaCl/2.5 mM KCl/0.12 mM MgSO4/40 mM Hepes, pH 7.4)
Binding Temp: RT°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
E F Neufeld et al. Aptamer-based endocytosis of a lysosomal enzyme. Proc. Natl. Acad. Sci. USA 105(2008): 15908-15913
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