Moenomycin A (C2) Aptamer Details

ID# 7494

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Structure

Chemistry

DNA

Target

Moenomycin A

Sequence (3-char table code)

G A C U/T

5'-rGprGprAprGprGpnUpnCprGprApnCpnCpnUpnCprGpnCprGpnCprGprAprGprGprAprGprGprGpnUprGprGprAprGprGprGpnUpnCprGpnUprAprGprAprGpnCprGpnCprGpnUprAprGprGprAprGprGp-3'

Molecular Weight: 25776.83

Extinction Coefficient: 514500

Binding Conditions / Buffer

Binding buffer: 20mM HEPES (pH 7.4), 150mM NaCl, and 5mM MgCl2

Binding Temp: RT°C

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Heike, S., et al. "Aptamers that bind to the antibiotic moenomycin A." Bioorganic & Medicinal Chemistry, 9 (2001): 2557-2563.

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