MCP-1 (ADR7) Aptamer Details

ID# 7463

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Structure

Chemistry

2'-F-RNA

Target

Monocyte chemoattractant protein-1 (mouse)

Sequence (3-char table code)

G A C U/T

5'-rGprGprGprAprGprGprApfCprGprApfUprGpfCprGprGprGprAprApfCpfUpfCprApfCpfCprGprGprGprAprAprGprAprAprGpfCpfCpfCprGpfUpfUpfCpfCprGpfUpfCprApfCprAprGprApfCprApfUprGpfUpfUpfCpfCprGpfCprApfUpfCprGpfUpfCpfCpfUpfCpfCpfCp-3'

Molecular Weight: 22580.5

Extinction Coefficient: 670700

Binding Conditions / Buffer

Selection Buffer (110 mM NaCl, 1 mM MgCl2, 20 mM HEPES (pH 7.0), 1 mM CaCl2, 5 mM KCl, 0.001% HSA, 0.05% Tween 20)

Binding Temp: 37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Rhodes, Andrew, et al. "The generation and characterisation of antagonist RNA aptamers to MCP-1." FEBS Letter, 506 (2001): 85-90.

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