Mango III A10U Aptamer Details
ID# 8021
Structure
Chemistry
RNA
Target
Thiazole Orange - Biotin (TO1-Biotin)
Category
Small Organic
Affinity (Kd)
1.7 nM
Length
45
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprCprAprCprGprUprAprCprGprAprAprGprGprAprAprGprGprUprUprUprGprGprUprAprUprGprUprGprGprUprAprUprAprUprUprCprGprUprAprCprGprUprGprCp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
140mM KCl, 1mM MgCl2, 10mM NaH2PO4 pH 7.2, 0.05% Tween-20
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Trachman, R. J., Autour, A., Jeng, S. C. Y., Abdolahzadeh, A., Andreoni, A., Cojocaru, R., … Ferré-D’Amaré, A. R. (2019). Structure and functional reselection of the Mango-III fluorogenic RNA aptamer. Nature Chemical Biology, 15(5), 472–479. doi:10.1038/s41589-019-0267-9
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