Malaria.1 Aptamer Details
ID# 8053
Structure
Chemistry
DNA
Target
Plasmodium falciparum
Category
Cells
Affinity (Kd)
60 nM
Length
135
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdCpdApdApdApdCpdGpdCpdGpdCpdTpdGpdGpdTpdTpdTpdGpdGpdApdApdTpdGpdCpdTpdTpdApdGpdApdGpdTpdTpdTpdGpdApdTpdCpdGpdApdTpdGpdCpdCpdTpdApdAp-3'
Molecular Weight: 13891.09
Extinction Coefficient: 483970
Binding Conditions / Buffer
Aptamer Binding buffer [AB buffer, RPMI-1640 (pH 7.2) supplemented with BSA (1 mg/mL, Sigma, St Louis, MO), yeast tRNA (0.1 mg/mL, Invitrogen), sheared salmon sperm DNA (0.1 mg/mL, Invitrogen)]
Binding Temp: RT°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Oteng, Eugene, et al. "High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes" Scientific Reports 10, 9706
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