M5 Aptamer Details
ID# 9590
Structure
Chemistry
DNA
Target
Mutant Q78 Huntingtin
Category
Protein
Affinity (Kd)
N/A nM
Length
36
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdApdGpdGpdGpdAp
Molecular Weight: 11645.5 g/mole
Extinction Coefficient: 393400
Binding Conditions / Buffer
Binding conditions were evaluated with a typical ELISA. Binding depletion type of ELISA was conducted to evaluate aptamer binding efficiency.
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Shin, B., Jung, R., Oh, H., Owens, G. E., Lee, H., Kwak, S., Lee, R., Cotman, S. L., Lee, J. M., MacDonald, M. E., Song, J. J., Vijayvargia, R., & Seong, I. S. (2018). Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity. Molecular therapy. Nucleic acids, 11, 416–428. https://doi.org/10.1016/j.omtn.2018.03.008
Request a Quote
Have your aptamer oligo synthesized by Aptagen.
