Lung Cancer Serum (Apt-43) Aptamer Details

ID# 10109

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Structure

Chemistry

DNA

Target

Lung cancer serum

Sequence (3-char table code)

G A C U/T

5'-dCpdTpdApdTpdApdGpdCpdApdApdTpdGpdGpdTpdApdCpdGpdGpdTpdApdCpdTpdTpdCpdCpdTpdCpdTpdCpdApdGpdGpdTpdGpdGpdGpdTpdGpdTpdApdTpdGpdTpdGpdGpdGpdCpdTpdCpdCpdCpdTpdTpdTpdApdCpdTpdGpdApdTpdTpdGpdGpdGpdTpdCpdApdApdApdApdGpdTpdGpdCpdApdCpdGpdCpdTpdApdCpdTpdTpdTpdGpdCpdTpdApdAp-3'

Molecular Weight: 27159.6 g/mole

Extinction Coefficient: 830300

Binding Conditions / Buffer

Phosphate-buffered saline (PBS) with 0.1% Tween-20

Binding Temp: Heated to 95°C for 5 min then cooled to 0°C for 10 min

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Li K, Xiu C-L, Gao L-M, et al. Screening of specific nucleic acid aptamers binding tumor markers in the serum of the lung cancer patients and identification of their activities. Tumor Biology. 2017;39(7). doi:10.1177/1010428317717123

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