Liver-Specific Ligands (236) Aptamer Details
ID# 7595
Structure
Chemistry
Peptide
Target
Liver-Specific Ligands
Category
Tissue
Affinity (Kd)
n/a nM
Length
7
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
NH2-GlnArgValLeuValLysLys-COOH
Molecular Weight: 916.24
Extinction Coefficient:
Binding Conditions / Buffer
Selection Buffer (PBS, 1 M NaCl, and 2% Triton X-100) Wash Buffers (0.1% Sodium Borohydride, 0.1 M Phosphate Buffer) (PBS, 5% BSA, 0.1% cold water fish gelatin, and 5% normal goat serum in PBS) Incubation Buffer (PBS and 1.1% BSA-C)
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ludtke et al. "In Vivo Selection and Validation of Liver-Specific Ligands Using a New T7 Phage Peptide Display System." Drug Delivery, 14(2007): 357-369.
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