Lipopolysaccharide (LPS) (Aptamer 19) Aptamer Details
ID# 10028
Structure
Chemistry
DNA
Target
Lipopolysaccharide (LPS)
Category
Other
Affinity (Kd)
Concentration 20 mmol/L, pH 7.35, Tris–HCl, 137 mmol/L NaCl, 5 mmol/L KCl, 2 mmol/L CaCl2, 1 mmol/L MgCl2
Length
84
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dTpdApdGpdGpdGpdApdApdTpdTpdCpdGpdTpdCpdApdCpdGpdGpdApdTpdCpdCpdGpdGpdCpdGpdTpdCpdCpdApdCpdTpdCpdCpdCpdApdGpdCpdCpdGpdCpdTpdCpdApdCpdTpdApdGpdTpdTpdTpdCpdTpdGpdCpdGpdTpdGpdGpdGpdTpdGpdApdCpdTpdGpdCpdApdGpdGpdTpdCpdGpdApdCpdGpdCpdApdTpdGpdCpdGpdCpdCpdGp-3'
Molecular Weight: 25852.7 g/mole
Extinction Coefficient: 771800
Binding Conditions / Buffer
37°C
Binding Temp: Incubated at 85°C for 20 min, placed on ice for 5 min, incubated at 37°C for 1 hour
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ai-qing Wen, Qing-wu Yang, Jing-cheng Li, Feng-ling Lv, Qi Zhong, Cai-yu Chen, A novel lipopolysaccharide-antagonizing aptamer protects mice against endotoxemia, Biochemical and Biophysical Research Communications, Volume 382, Issue 1,
2009, Pages 140-144, ISSN 0006-291X,
https://doi.org/10.1016/j.bbrc.2009.02.152.
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