Lectin concanavalin A (Con A-3-1m) Aptamer Details

ID# 10082

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Structure

Chemistry

DNA

Target

Lectin concanavalin A

Sequence (3-char table code)

G A C U/T

5'-dGpdApdTpdCpdCpdCpdApdGpdTpdCpdCpdGpdApdApdGpdTpdApdApdTpdCpdGpdTpdTpdGpdCpdApdTpdCpdTpdGpdCpdApdCpdGpdApdCpdTpdGpdGpdTpdGpdApdGpdCpdTpdTpdGpdApdGpdTpdGpdGpdCpdApdGpdApdApdGpdApdCpdTpdTpdGpdTpdGpdCpdApdApdApdCpdGpdGpdCpdTpdApdTpdApdGpdGp-3'

Molecular Weight: 780200 L/(mole·cm)

Extinction Coefficient: 780200 L/(mole·cm)

Binding Conditions / Buffer

Incubated with Con A and FITC-PSA (counter-target, Kd = > 1 μM) in selection buffer (1xPBS, 2.5 mM MgCl2, 1mM CaCl2, 0.01% Tween 20)

Binding Temp: Room Temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Chelsea K. L. Gordon, Diana Wu, Anusha Pusuluri, Trevor A. Feagin, Andrew T. Csordas, Michael S. Eisenstein, Craig J. Hawker, Jia Niu, Hyongsok Tom Soh; Click-Particle Display for Base-Modified Aptamer Discovery. ACS Chem. Biol. 20 December 2019; 14 (12): 2652–2662. https://doi.org/10.1021/acschembio.9b00587

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