L-Tyrosinamide (pe35) Aptamer Details
ID# 7519
Structure
Chemistry
DNA
Target
L-Tyrosinamide
Category
Small Organic
Affinity (Kd)
45 µM
Length
49
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdTpdTpdCpdGpdCpdTpdApdGpdCpdTpdGpdGpdApdGpdCpdTpdTpdGpdGpdApdTpdTpdGpdApdTpdGpdTpdGpdGpdTpdGpdTpdGpdTpdGpdApdGpdTpdGpdCpdGpdGpdTpdGpdCpdCpdCp-3'
Molecular Weight: 15261.94
Extinction Coefficient: 463600
Binding Conditions / Buffer
Binding Buffer (20 mM Tris (pH 7.6), 300 mM NaCl, 5 mM MgCl2)
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Vianini et al. "In vitro selection of DNA aptamers that bind L-tyrosinamide." Bioorganic & Medicinal Chemistry, 9 (2001): 2543-2548.
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