L-Selectin Multivalent Aptamer Aptamer Details
ID# 7951
Structure
Chemistry
DNA
Target
L-Selectin
Category
Protein
Affinity (Kd)
(Multivalent) 0.75 nM
Length
49
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dTpdApdGpdCpdCpdApdApdGpdGpdTpdApdApdCpdCpdApdGpdTpdApdCpdApdApdGpdGpdTpdGpdCpdTpdApdApdApdCpdGpdTpdApdApdTpdGpdGpdCpdTpdTpdCpdGpdGpdCpdTpdTpdApdCp
Molecular Weight: 15113.89
Extinction Coefficient: 481400
Binding Conditions / Buffer
PBS
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Chang EK, Eckert MA, Ali MM, Riazifar H, Pone EJ, Liu L, et al. (2015) Facile Supermolecular Aptamer Inhibitors of L-Selectin. PLoS ONE 10(3): e0123034. doi:10.1371/journal.pone.0123034
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