L-apt3.1 Aptamer Details
ID# 9735
Structure
Chemistry
L-RNA
Target
poly(UG) (pUG) fold D-rG4
Category
Other
Affinity (Kd)
13.5 ± 2.8 nM
Length
29
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-LrGLrCLrCLrGLrCLrALrCLrULrGLrGLrULrGLrGLrGLrULrCLrGLrGLrULrGLrGLrGLrALrALrGLrCLrGLrGLrC
Molecular Weight: 9000.7 g/mole
Extinction Coefficient: 267000
Binding Conditions / Buffer
25 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 150 mM KCl
Binding Temp: Denature at 95°C for 5 minutes then cool to room temperature.
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Shiau Wei Liew, Dong Cao, Riley J Petersen, Samuel E Butcher, Scott G Kennedy, Chun Kit Kwok, A novel L-RNA aptamer to regulate the pUG fold RNA-induced gene expression in vivo, Nucleic Acids Research, Volume 53, Issue 5, 24 March 2025, gkaf137, https://doi.org/10.1093/nar/gkaf137
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