L-Apt12-6 Aptamer Details
ID# 9762
Structure
Chemistry
L-RNA
Target
c-kit 1 D-dG4
Category
Other
Affinity (Kd)
42.3 ± 1.9 nM
Length
32
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-LrCLrGLrCLrCLrGLrCLrCLrGLrGLrGLrULrALrULrGLrALrGLrGLrGLrALrGLrGLrALrGLrGLrGLrGLrGLrCLrGLrGLrCLrG-3'
Molecular Weight: 10050.4 g/mole
Extinction Coefficient: 308400
Binding Conditions / Buffer
25 mM Tris-HCl (pH 7.5), 10 mM MgCl2, 150 mM KCl
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ji D, Yuan JH, Chen SB, Tan JH, Kwok CK. Selective targeting of parallel G-quadruplex structure using L-RNA aptamer. Nucleic Acids Res. 2023 Nov 27;51(21):11439-11452. doi: 10.1093/nar/gkad900. PMID: 37870474; PMCID: PMC10681708.
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