L-Apt.G3 Aptamer Details
ID# 9733
Structure
Chemistry
L-RNA
Target
c-kit 1 D-dG4
Category
Other
Affinity (Kd)
8.8 ± 1.5 nM
Length
32
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-LrCLrGLrALrULrGLrCLrULrGLrALrCLrGLrCLrGLrGLrGLrCLrGLrGLrGLrALrGLrGLrGLrALrGLrALrGLrCLrALrULrCLrG-3'
Molecular Weight: 9979.4 g/mole
Extinction Coefficient: 309100
Binding Conditions / Buffer
25 mM Tris-HCl (pH 7.5), 10 mM MgCl2, 150 mM KCl
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wu, T.-Y., & Kwok, C. K. (2025). G4-SLSELEX-seq-driven discovery of a G4-specific targeting L-RNA aptamer with unique structural features. Organic & Biomolecular Chemistry, 23(43), 9851–9856. https://doi.org/10.1039/d5ob00526d
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