L-Apt.1-1 Aptamer Details
ID# 9759
Structure
Chemistry
L-RNA
Target
APP D-rG4
Category
Other
Affinity (Kd)
12.48 ± 2.82 nM
Length
30
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-LrGLrULrGLrULrALrULrALrGLrALrULrGLrGLrGLrALrALrALrGLrGLrGLrULrULrCLrULrALrULrALrCLrGLrCLrA-3'
Molecular Weight: 9237.9 g/mole
Extinction Coefficient: 298900
Binding Conditions / Buffer
25 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 150 mM KCl
Binding Temp: Slow cooling from 95 °C to 4 °C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Lau, H. L., Zhao, H., Feng, H., & Kwok, C. K. (2025). Specific Targeting and Imaging of RNA G-Quadruplex (rG4) Structure Using Non-G4-Containing l-RNA Aptamer and Fluorogenic l-Aptamer. Small methods, 9(3), e2401097. https://doi.org/10.1002/smtd.202401097
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