Interleukin-6 receptor (AIR-3A) Aptamer Details
ID# 7839
Structure
Chemistry
RNA
Target
Cells presenting IL-6R
Category
Cells
Affinity (Kd)
8.5 nM
Length
19
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprGprAprGprGprCprUprGprUprGprGprUprGprAprGprGprGp-3'
Molecular Weight: 6307.88
Extinction Coefficient: 193400
Binding Conditions / Buffer
Selection Buffer (used for Filter Retention Assay): 137 mM NaCl, 2.7 mM KCl, 6.5 mM Na2HPO4, and 3 mM MgCl2 at PH 7.5.
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Meyer C, U Hahn, et al. (2012) Interleukin-6 Receptor specific RNA aptamers for cargo delivery into target cells. RNA Biol
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