Interleukin-6 receptor (AIR-3) Aptamer Details
ID# 7838
Structure
Chemistry
RNA
Target
Soluable interleukin-6 receptor (sIL-6R)
Category
Protein
Affinity (Kd)
19.7 nM
Length
106
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprAp rAprGprAp rAprAprGp rAprGprGp rUprCprUp rGprAprGp rAprCprAp rUprUprCp rUp rCprUprUp rAprUprAp rGprGprGp rGprAprGp rGprCprUp rGprUprGp rGprUprGp rAprGprGp rGprAprAp rUprAprUp rUprAprAp rGprAprGp rAprAprUp rUprAprAp rCprGprGp rUprCprUp rAprGprUp rUprCprAp rCprCprUp rCprGprAp rCprUprUp rCprUprGp rGprAprGp rUprUprGp rAprCprGp rUprUprGp rCprUprUp-3'
Molecular Weight: 34310.65
Extinction Coefficient: 1085700
Binding Conditions / Buffer
Selection Buffer (used for Filter Retention Assay): 137 mM NaCl, 2.7 mM KCl, 6.5 mM Na2HPO4, and 3 mM MgCl2 at PH 7.5.
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Meyer C, U Hahn, et al. (2012) Interleukin-6 Receptor specific RNA aptamers for cargo delivery into target cells. RNA Biol
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