IL-6 Aptamer Aptamer Details
ID# 8228
Structure
Chemistry
DNA
Target
Interleukin 6 (IL-6)
Category
Protein
Affinity (Kd)
Not given nM
Length
31
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdTpdGpdGpdCpdApdGpdGpdApdGpdGpdApdCpdTpdApdTpdTpdTpdApdTpdTpdTpdGpdCpdTpdTpdTpdTpdCpdTp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
1X PBS or a buffer of [20 mM Tris-HCl (pH 7.2), 140 mM NaCl, 5 mM KCl]. The aptamer can form a G-quadruplex in the presence of K+ ions.
Binding Temp: 4-23°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
"A flexible multiplexed immunosensor for point-of-care in situ wound monitoring", Yuji Gao, et. al. (2021)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139589/pdf/abg9614.pdf
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