HupB-13T Aptamer Details
ID# 8807
Structure
Chemistry
DNA
Target
HupB (Rv2986c)
Category
Protein
Affinity (Kd)
∼0.17 µM
Length
11
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdGpdGpdGpdGpdGpdGpdApdGpdGp-3'
Molecular Weight: 3543.3
Extinction Coefficient: 115600
Binding Conditions / Buffer
10 mM Tris pH 7.5, 10 mM MgCl2, 50 mM KCl, 25 mM NaCl
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Kalra, P., et al. "G-Quadruplex-Forming DNA Aptamers Inhibit the
DNA-Binding Function of HupB andMycobacterium
tuberculosis Entry into Host Cells." Molecular Therapy: Nucleic Acids. Vol. 13. December 2018. https://doi.org/10.1016/j.omtn.2018.08.011
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