Human Norovirus SMV-21 Aptamer Details
ID# 7932
Structure
Chemistry
DNA
Target
Human Norovirus
Category
Other
Affinity (Kd)
101 nM
Length
81
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dApdGpdTpdApdTpdApdCpdGpdTpdApdTpdTpdApdCpdCpdTpdGpdCpdApdGpdCp dCpdCpdApdTpdGpdTpdTpdTpdTpdGpdTpdApdGpdGpdTpdGpdTpdApdApdTpdApdGpdGpdTpdCpdApdTpdGpdTpdTpdApdGpdGpdGpdTpdTpdTpdCpdTpdGp dCpdGpdApdTpdApdTpdCpdTpdCpdGpdGpdApdGpdApdTpdCpdTpdTpdGpdCp
Molecular Weight: 25046.34
Extinction Coefficient: 781000
Binding Conditions / Buffer
500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature
Binding Temp: 24°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Escudero-Abarca BI, Suh SH, Moore MD, Dwivedi HP, Jaykus L-A (2014) Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains. PLoS ONE 9(9): e106805. doi:10.1371/journal.pone.0106805
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