Human Influenza A virus H3N2 (P30-10-16) Aptamer Details
ID# 7527
Structure
Chemistry
RNA
Target
Human Influenza A virus H3N2
Category
Cells
Affinity (Kd)
0.188 nM
Length
74
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprAprGprAprAprUprUprCprCprGprAprCprCprAprGprAprAprGprGprGprUprUprAprGprCprAprGprUprCprGprGprCprAprUprGprCprGprGprUprAprCprAprGprAprCprAprGprAprCprCprUprUprUprCprCprUprCprUprCprUprCprCprUprUprCprCprUprCprUprUprCprUp-3'
Molecular Weight: 23621.16
Extinction Coefficient: 710100
Binding Conditions / Buffer
Binding Buffer (20 nM HEPES/KOH (pH 7?ú4), 105 mM NaCl) PIPES buffer (5 mM PIPES/NaOH, 145 mM NaCl (pH 7?ú5)) Acidic buffer (145 mM NaCl, 20 mM sodium citrate, 1 U RNase inhibitor µl-1 (pH 5?ú0))
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Gopinath, S., et al. "An RNA aptamer that distinguishes between closely related human influenza viruses and inhibits haemagglutinin-mediated membrane fusion." Journal of General Virology, 87(2005): 479-487.
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