Human IL-23 Aptamer A23P3 Aptamer Details
ID# 8950
Structure
Chemistry
DNA
Target
Human IL-23 (P19 subunit used for SELEX)
Category
Protein
Affinity (Kd)
1.37 nM
Length
80
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdCpdTpdGpdTpdGpdTpdGpdApdCpdTpdCpdCpdTpdGpdCpdApdApdCpdCpdGpdApdCpdTpdGpdGpdApdGpdCpdApdCpdCpdGpdTpdCpdTpdGpdApdGpdGpdGpdTpdApdCpdApdCpdApdCpdGpdCpdCpdTpdApdTpdGpdApdCpdCpdTpdGpdTpdGpdCpdApdGpdCpdTpdGpdTpdApdTpdGpdTpdTpdGpdTpdCpdTpdCpdCp
Molecular Weight: 26400
Extinction Coefficient:
Binding Conditions / Buffer
50 mM phosphate buffer, 300 mM NaCl, room temperature
Binding Temp: Heat at 95°C for 5 min, then cool at room temperature for 30 min.
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Rezaee MA, Shobeiri SS, Moghadam M, Mashayekhi K, and Sankian M. In vitro identification of single-stranded DNA aptamers targeting human IL-23 using the protein-SELEX strategy. J Pharm Biomed Anal 2024, 247, 116245. https://doi.org/10.1016/j.jpba.2024.116245
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