Aptagen

Human Breast Cancer Xenografts (RGD-4C) Aptamer Details

ID# 7608
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Structure
Human Breast Cancer Xenografts (RGD-4C) structure
Chemistry
Peptide
Target
Human Breast Cancer Xenografts
Category
Tissue
Affinity (Kd)
N/A nM
Length
9
Aptazyme
No

Sequence (3-char table code)

G A C U/T
NH2-CysAspCysArgGlyAspCysPheCys-COOH
Molecular Weight: 1103.34
Extinction Coefficient:

Binding Conditions / Buffer

In vivo mice.
Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Arap et al. "Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model." Science, 279(1998): 377-380.
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