Human Angiopoietin-2 (R4-002) Aptamer Details
ID# 10113
Structure
Chemistry
DNA
Target
Human angiopoietin-2 (Ang2)
Category
Protein
Affinity (Kd)
20.5 ± 7.3 nM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdCpdTpdTpdGpdTpdApdGpdGpdGpdTpdTpdCpdGpdGpdCpdTpdGpdGpdTpdCpdApdGpdGpdGpdTpdGpdTpdCpdCpdApdApdGpdTpdCpdTpdGpdTpdGpdGp-3'
Molecular Weight: 12446 g/mole
Extinction Coefficient: 379500
Binding Conditions / Buffer
20 mM Hepes,150 mM NaCl, 1 mM MgCl2, 1 mM CaCl2, pH 7.4
Binding Temp: Room temperature°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
M. Cho,S. Soo Oh,J. Nie,R. Stewart,M. Eisenstein,J. Chambers,J.D. Marth,F. Walker,J.A. Thomson, & H.T. Soh,
Quantitative selection and parallel characterization of aptamers, Proc. Natl. Acad. Sci. U.S.A. 110 (46) 18460-18465, https://doi.org/10.1073/pnas.1315866110 (2013).
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