HPA-2 Aptamer Details
ID# 8107
Structure
Chemistry
DNA
Target
Helicobacter pylori
Category
Other
Affinity (Kd)
19.3 ± 3.2 nM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdCpdApdGpdGpdApdGpdGpdApdCpdCpdCpdTpdApdTpdTpdCpdTpdCpdGpdTpdGpdTpdApdTpdCpdGpdApdCpdGpdApdGpdApdTpdCpdCpdApdGpdTpdGp-3'
Molecular Weight: 12297
Extinction Coefficient: 385700
Binding Conditions / Buffer
100 mM NaCl, 5 mM KCl, 50 mM Tris−HCl, and 1 mM MgCl2, pH 7.5
Binding Temp: 30°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wu, Hangjie et al. “Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA Aptamers.” ACS omega vol. 6,5 3771-3779. 21 Jan. 2021, doi:10.1021/acsomega.0c05374
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