HM20 against Morphine-Like Opioids Aptamer Details
ID# 9301
Structure
Chemistry
DNA
Target
Morphine-Like Opioids
Category
Small Organic
Affinity (Kd)
1.11 ± 0.06 µM
Length
46
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdGpdApdCpdGpdApdCpdApdTpdGpdCpdGpdTpdCpdGpdApdApdApdApdGpdApdCpdCpdCpdCpdTpdGpdApdGpdGpdGpdCpdApdGpdCpdTpdGpdGpdTpdCpdGpdTpdCpdCpdCp-3'
Molecular Weight: 14211.2 g/mole
Extinction Coefficient: 438900
Binding Conditions / Buffer
10 mM Tris−HCl (pH 7.4), 20 mM NaCl, and 0.5 mM MgCl2
Binding Temp: 25 °C °C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Canoura, J., Alkhamis, O., Venzke, M., Ly, P. T., & Xiao, Y. (2024). Developing Aptamer-Based Colorimetric Opioid Tests. JACS Au, 4(3), 1059–1072. https://doi.org/10.1021/jacsau.3c00801
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