Histone H3R8Me2sym (Clone 1) Aptamer Details

ID# 7615

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Structure

Chemistry

RNA

Target

Histone H3R8Me2sym

Sequence (3-char table code)

G A C U/T

5'-rGprGprGprAprCprGprCprGprUprGprGprUprAprCprCprGprAprUprGprGprGprUprCprAprGprCprAprUprGprUprAprGprCprCprAprGprGprCprAprGprGprGprCprCprGprUprGprUprGprAprGprCprUprUprGprUprGprCprUprGprAprUprGprUprGprAprGprCprUprUprCprCprGprCprGprGprGprGprAprUprCp-3'

Molecular Weight: 26323.83

Extinction Coefficient: 784200

Binding Conditions / Buffer

Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Hyun et al. "An RNA Aptamer That Selectively Recognizes Symmetric Dimethylation of Arginine 8 in the Histone H3 N-Terminal Peptide." Nucleic Acid Therapeutics, 21 (2011): 157-163.

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