HGF (H38-15) Aptamer Details
ID# 7464
Structure
Chemistry
DNA
Target
Human Hepatocyte Growth Factor
Category
Protein
Affinity (Kd)
19 nM
Length
102
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdGpdApdTpdGpdCpdCpdTpdGpdTpdCpdCpdApdGpdCpdApdTpdCpdGpdApdGpdCpdGpdCpdCpdApdGpdCpdTpdTpdTpdGpdCpdTpdGpdApdTpdGpdGpdGpdTpdGpdGpdCpdCpdApdCpdCpdCpdTpdTpdGpdCpdCpdCpdTpdGpdGpdGpdTpdTpdTpdGpdApdApdTpdTpdTpdCpdGpdApdTpdCpdCpdTpdApdTpdCpdGpdGpdTpdApdGpdCpdTpdApdGpdApdCpdTpdGpdCpdTpdTpdTpdGpdTpdCpdCpdTpdCpdGp-3'
Molecular Weight: 31366.29
Extinction Coefficient: 928300
Binding Conditions / Buffer
Binding Buffer (PBS containing 1 mM MgCl2)
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Saito, Takesh et al. "Generation of Inhibitory DNA Aptamers Against Human Hepatocyte Growth Factor." DNA and Cell Biology, 24 (2005): 624-633.
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