HBA1 Aptamer Details
ID# 8130
Structure
Chemistry
DNA
Target
Avian Influenza Virus Subtype H5N1
Category
Other
Affinity (Kd)
70 nM
Length
60
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5’-dApdTpdGpdCpdGpdGpdApdTpdCpdCpdCpdGpdCpdGpdCpdGpdCpdGpdApdCpdCpdGpdTpdGpdTpdCpdApdGpdCpdGpdGpdGpdGpdApdCpdTpdApdGpdCpdGpdGpdTpdGpdTpdApdGpdCpdGpdCpdGpdApdApdGpdCpdTpdTpdGpdCpdGpdCp-3’
Molecular Weight: 18601
Extinction Coefficient: 559900
Binding Conditions / Buffer
Tris buffer (20 mM, pH 7.4).
Binding Temp: Not given.°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Kim, S.; Choi, J.; Kim, A.; Lee, S.; Yoon, M. Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1. Biomolecules 2020 July 28; 10(8): 1116. DOI: 10.3390/biom10081116.
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