Aptagen

HA 12-16 Aptamer Details

ID# 7893
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Structure
HA 12-16 structure
Chemistry
RNA
Target
HA protein (gHA1)
Category
Protein
Affinity (Kd)
20 mM sodium phosphate, pH 7.5, 500 mM NaCl and 20 mM imidazole
Length
94
Aptazyme
No

Sequence (3-char table code)

G A C U/T
dGpdGpdGpdTpdTpdCpdApdCpdTpdGpdCpdApdGpdApdCpdTpdTpdGpdApdCpdGpdApdApdGpdCpdTpdTpdGpdCpdTpdTpdGpdApdCpdGpdGpdApdGpdApdTpdCpdApdApdGpdGpdGpdCpdGpdApdGpdTpdCpdTpdCpdApdTpdApdCpdCpdApdApdGpdTpdTpdGpdApdTpdGpdGpdGpdGpdApdApdTpdGpdGpdApdTpdCpdCpdApdCpdApdTpdCpdTpdApdCpdGpdApdApdTpdTpdCp
Molecular Weight: 29132.96
Extinction Coefficient: 915800

Binding Conditions / Buffer

23°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Kwon, H. et al. "An RNA Aptamer That Specifically Binds to the Glycosylated Hemagglutinin of Avian Influenza Virus and Suppresses Viral Infection in Cells." PLOS One 2014, 9 1-9.
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