GWDB-30 Aptamer Details
ID# 8042
Structure
Chemistry
DNA
Target
Calreticulin
Category
Protein
Affinity (Kd)
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Length
78
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdCpdGpdTpdTpdCpdGpdGpdApdTpdCpdGpdCpdApdCpdTpdApdGpdApdGpdCpdCpdCpdApdApdApdTpdCpdTpdCpdApdGpdApdApdApdCpdCpdCpdApdTpdTpdCpdTpdCpdTpdApdCpdApdCpdApdCpdCpdTpdTpdGpdTpdApdCpdCpdTpdTpdCpdTpdGpdApdApdCpdGpdTpdTpdCpdTpdCpdApdCpdGpdCpdAp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
Target unclear. References are made to binding calprotectin as well as calreticulin. These are structurally unrelated proteins. 30 sequences are listed, it is unknown which of these have been validated.
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
https://patents.google.com/patent/CN105063056A/en
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