GR-3 Aptamer Details
ID# 7984
Structure
Chemistry
DNA
Target
glucagon receptor (GCGR)
Category
Protein
Affinity (Kd)
52.7?ñ5.1 nM
Length
78
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
3'-dApdTpdCpdCpdApdGpdApdGpdTpdGpdApdCpdGpdCpdApdGpdCpdApdGpdApdTpdApdApdGpdTpdApdGpdGpdTpdApdTpdCpdCpdGpdTpdTpdTpdGpdApdApdApdApdApdCpdTpdTpdTpdTpdCpdTpdGpdApdCpdCpdGpdTpdCpdCpdGpdApdCpdTpdApdTpdGpdGpdApdCpdApdCpdGpdGpdTpdGpdGpdCpdTpdTpdApdGpdTp-5'
Molecular Weight: 24099.71
Extinction Coefficient: 760100
Binding Conditions / Buffer
5mM MgCl2 and 4.5 g/L glucose in Dulbeccoƒ??s Phosphate Bufered Saline (D-PBS, pH=7.4), and 0.1mg/mL yeast tRNA and 1mg/L bovine serum albumin (BSA) to reduce nonspecifc binding.
Binding Temp: 4-37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wang, Guodong, et al. "Selection and characterization of DNA aptamer against glucagon receptor by cell-SELEX". Nature: Scientific Reports (7): 7179. DOI:10.1038/s41598-017-05840-w
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