GNP DV2 Aptamer Details
ID# 8072
Structure
Chemistry
DNA
Target
Dichlorvos (DV)
Category
Small Organic
Affinity (Kd)
0.85 nM
Length
65
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5’-dGpdGpdApdApdGpdApdApdCpdApdTpdGpdTpdGpdApdGpdCpdApdApdApdApdGpdGpdCpdCpdApdGpdCpdApdApdApdApdGpdGpdCpdCpdApdGpdGpdApdApdCpdCpdGpdTpdApdApdApdApdApdGpdGpdCpdCpdGpdCpdGpdTpdTpdGpdCpdTpdGpdGpdCpdGp-3’
Molecular Weight: 20258.2
Extinction Coefficient: 655400
Binding Conditions / Buffer
10 mM Tris, 10 mM MgCl2, 50 mM KCl, 25 mM NaCl, pH 7.5
Binding Temp: 25°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Chatterjee, B., Kalyani, N., Anand, A., Khan, E., Das, S., Bansal, V., … Sharma, T. K. (2020). GOLD SELEX: a novel SELEX approach for the development of high-affinity aptamers against small molecules without residual activity. Microchimica Acta, 187(11). doi:10.1007/s00604-020-04577-0
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