Aptagen

Glucose-bisboronic acid aptamer-sensor Aptamer Details

ID# 8045
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Structure
Glucose-bisboronic acid aptamer-sensor structure
Chemistry
DNA
Target
Glucose
Category
Small Organic
Affinity (Kd)
5 nM
Length
44
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dCpdTpdCpdTpdCpdGpdGpdGpdApdCpdGpdApdCpdApdGpdCpdCpdGpdApdGpdTpdTpdGpdApdTpdTpdCpdApdApdCpdApdGpdCpdCpdGpdApdGpdTpdCpdGpdTpdCpdCpdCp-3'
Molecular Weight: 13478.75
Extinction Coefficient: 453870

Binding Conditions / Buffer

Shinkai's receptor 50uM with 2% methanol.
Binding Temp: 24 °C°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058
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