GL21.T Aptamer Details
ID# 7907
Structure
Chemistry
RNA
Target
Axl tyrosine kinase receptor
Category
Protein
Affinity (Kd)
12 nM
Length
34
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rApfUprGprApfUpfCprAprApfUpfCprGpfCpfCpfUpfCprAprApfUpfUpfCprGprApfCprAprGprGprAprGprGpfCpfUpfCprApfCp-3'
Molecular Weight: 10875.53
Extinction Coefficient: 335000
Binding Conditions / Buffer
Dulbecco's Modified Eagle's Medium (DMEM), 10% FBS, 2mM L-glutamine
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Laura Cerchia, Carla L Esposito, Simona Camorani, Anna Rienzo, Loredana Stasio, Luigi Insabato, Andrea Affuso and Vittorio de Franciscis,"Targeting Axl With an High-affinity Inhibitory Aptamer". Molecular Therapy vol.20 no.12, 2291-2303, Dec2012.
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