GBN2 Aptamer Details
ID# 8110
Structure
Chemistry
DNA
Target
Nervous necrosis virus (NNV)
Category
Other
Affinity (Kd)
27.96 nM
Length
95
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5’-dGpdApdCpdGpdCpdTpdTpdApdCpdTpdCpdApdGpdGpdTpdGpdTpdGpdApdCpdTpdCpdGpdCpdTpdCpdCpdApdCpdTpdGpdGpdTpdCpdCpdGpdGpdApdTpdCpdApdCpdTpdTpdGpdApdTpdApdTpdGpdTpdCpdGpdTpdGpdCpdGpdGpdCpdApdGpdTpdCpdGpdTpdTpdTpdApdCpdApdTpdCpdCpdCpdGpdApdApdGpdGpdApdCpdGpdCpdApdGpdApdTpdGpdApdApdGpdTpdCpdTpdCp-3’
Molecular Weight: 29267.9
Extinction Coefficient: 894300
Binding Conditions / Buffer
5 g/L glucose,10% FBS, 1.0 g/L bovine serum albumin, 0.1 mg/ml yeast tRNA and 5 mM MgCl2
Binding Temp: 4°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Zhou L, Wang S, Yu Q, et al. Characterization of Novel Aptamers Specifically Directed to Red-Spotted Grouper Nervous Necrosis Virus (RGNNV)-Infected Cells for Mediating Targeted siRNA Delivery. Front Microbiol. 2020;11:660. Published 2020 Apr 30. doi:10.3389/fmicb.2020.00660
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