Gastrin-Releasing Peptide (GRP-1) Aptamer Details
ID# 7751
Structure
Chemistry
Peptide
Target
Gastrin-Releasing Peptide Receptor (GRPR) aka BB2 Receptor)
Category
Protein
Affinity (Kd)
N/A nM
Length
12
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
CysGlyGlyAsnHisTrpAlaValGlyHisLeuMet
Molecular Weight: 1417.7
Extinction Coefficient:
Binding Conditions / Buffer
Peptide binding assays: Phosphate-buffered saline (PBS) with 1% fetal calf serum (FCS).
Binding Temp: RT°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
M Sioud et al. Efficient siRNA targeted delivery into cancer cells by gastrin-releasing peptides. Bioconjugate Chem 23(2012): 1040-1049.
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