FANA R8-3 Aptamer Details
ID# 8173
Structure
Chemistry
Chimeric
Target
SARS-CoV-2 S Protein
Category
Protein
Affinity (Kd)
68.1 nM
Length
79
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdApdApdGpdGpdTpdApdGpdTpdGpdCpdTpdGpdApdApdTpdTpdCpdGpdGpdTpdCpdGpdCpdGpdApdTpdTpdApdApdCpdApdTpdTpdApdApdApdCpdCpdGpdCpdApdTpdApdApdApdApdApdGpdGpdGpdTpdGpdGpdCpdCpdGpdGpdApfUpfUpfCpfGpfCpfUpfApfUpfCpfCpfApfGpfUpfUpfGpfGpfCpfCpfUp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
Buffer: 200 µl PBS (137 mM NaCl, 2.7 mM KCl, 8 mM Na2HPO4, and 2 mM KH2PO4)
pH: 7.4
Incubation time: 30 mins
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ferreira-Bravo, I. A. and J. J. DeStefano. 2021. Xeno-nucleic Acid (XNA) 2'-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding. bioRxiv
https://doi.org/10.1101/2021.07.13.452259
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