EGFR (CL4) Aptamer Details
ID# 7811
Structure
Chemistry
2'-F-RNA
Target
EGFR - Extracellular Domain
Category
Protein
Affinity (Kd)
10 nM
Length
39
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGpfCpfCpfUpfUprAprGpfUprAprApfCprGpfUprGpfCpfUpfUpfUprGprApfUprGpfUpfCprGprApfUpfUpfCprGprApfCprAprGprGprAprGprGpfCp-3'
Molecular Weight: 12561.44
Extinction Coefficient: 386200
Binding Conditions / Buffer
Buffer used for Binding Assays: PBS with 0.01% BSA. Incubation Time: 15 minutes.
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
CL Esposito et al. A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death. PLoS One 6(2011):e24071.
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