E-Selectin Aptamer Details
ID# 7658
Structure
Chemistry
Peptide
Target
E-Selectin
Category
Protein
Affinity (Kd)
4 nM
Length
12
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
NH2-AspIleThrTrpAspGlnLeuTrpAspLeuMetLys-COOH
Molecular Weight: 1699.99
Extinction Coefficient:
Binding Conditions / Buffer
Assay Buffer (PBS, 0.1% BSA, 424 µM Ca(NO3)2, 406 µM MgSO4, 0.02% Tween 20), 4 °C.
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Martens et al. "Peptides Which Bind to E-selectin and Block Neutrophil Adhesion." The Journal of Biological Chemistry, 270 (1995):21129-21136.
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