DTA-64 Aptamer Details
ID# 7978
Structure
Chemistry
DNA
Target
DEK
Category
Protein
Affinity (Kd)
N/A µM
Length
41
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdGpdGpdTpdTpdApdApdApdTpdApdTpdTpdCpdCpdCpdApdCpdApdTpdTpdGpdCpdCpdTpdGpdCpdGpdCpdCpdApdGpdTpdApdCpdApdApdApdTpdApdGp-3'
Molecular Weight: 12593.25
Extinction Coefficient: 399100
Binding Conditions / Buffer
Binding buffer (20 mM Tris pH 7.6; 100 mM NaCl; 5 mM MgCl2); Room Temperature (30 min - 1 hr, depending on round of testing).
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
N Mor-Vaknin et al. DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. Nature Communications 8(2017): 14252.
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